PUBLICATIONS
If you cannot access a manuscript via the provided links, please contact us and we will do our best to get it to you.
Naghavi NH, Kerfoot SM, and Shooshtari P (2024). Integrative Data Analysis to Uncover Transcription Factors Involved in Gene Dysregulation of Nine Autoimmune and Inflammatory Diseases. Submitted
NOTE: The preprint is free, but has not undergone peer review.
Tesfagiorgis Y*, Kemal EA*, Craig HC, Parham KA, and Kerfoot SM. (2024) Systemic administration of anti-CD20 indirectly reduces B cells in the inflamed meninges in a chronic model of central nervous system autoimmunity. Journal of Neuroimmunology 387: 578267.
*authors contributed equally
NOTE: The preprint is free, but has not undergone peer review. The journal link provides the final version.
Sanchez-Pupo RE, Finch GA, Johnston DE, Craig H, Abdo R, Barr K, Kerfoot S, Dagnino L, and Penuela S. (2024) Global Pannexin 1-deletion increases tumor-infiltrating lymphocytes in the BRAF/Pten mouse melanoma model. Molecular Oncology 18(4): 969-987
NOTE: The preprint is free, but has not undergone peer review. The journal link provides the final version.
Shin AE, Tesfagiorgis Y, Larsen F, Derouet M, Zeng PYF, Good HJ, Zhang L, Rubinstein MR, Han YW, Kerfoot SM, Nicholas AC, Hayakawa Y, Howlett CJ, Wang TC, and Asfaha S. (2023) F4/80+Ly6Chigh macrophages initiate tumorigenesis in inflammation-associated cancer. Gastroenterology 164(4):593-609.e13
Parham KA, Tan XXS, Morelli DM, Chowdhury L, Craig HC, and Kerfoot SM. (2022) Pre-germinal center interactions with T cells are natural checkpoints to limit autoimmune B cell responses. Journal of Immunology 209(9):1703-1712
Tuffs SW, Goncheva MI, Xu SX, Craig HC, Kasper KJ, Choi J, Flannagan RS, Kerfoot SM, Heinrichs DE, and McCormick JK. (2022) Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production. PNAS: 119 (8) e2115987119
NOTE: The preprint is free, but has not undergone peer review. The journal link provides the final version.
Al, KF, Craven LJ, Gibbons S, Parvathy SN, Wing AC , Graf C, Parham KP, Kerfoot SM, Wilcox H, Burton JP, Kremenchutzky M, Morrow SA, Casserly, Meddings JC, Sharma M, and Silverman MS. (2022) Fecal microbiota transplantation is safe and tolerable in patients with multiple sclerosis: A pilot randomized controlled trial. Multiple Sclerosis Journal - Experimental, Translational and Clinical 8: 20552173221086664.
Lancien, M, Bienvenu G, Salle S, Gueno L, Feyeux M, Merieau E, Remy S, Even A, Moreau A, Molle A, Fourgeux C, Coulon F, Beriou G, Bouchet-Delbos L, Chiffoleau E, Kirstetter P, Chan S, Kerfoot SM, Rahiman SA, Simone VD, Matteoli G, Boncompain G, Perez F, Josien R, Poschmann J, Cuturi MC, and Louvet C. (2021) Dendritic Cells Require TMEM176A/B Ion Channels for Optimal MHC Class II Antigen Presentation to Naive CD4+ T Cells. Journal of Immunology 207: 421–435.
Laramée AS, Raczkowski HL, Shao P, Batista CR, Shukla D, Xu LS, Haeryfar SMM, Tesfagiorgis Y, Kerfoot SM and DeKoter RP (2020). Opposing roles for the related ETS-family transcription factors Spi-B and Spi-C in regulating B cell differentiation and function. Frontiers in Immunology: 11:841
Haberman A, Gonzalez D, Wong P, Zhang T, and Kerfoot SM. (2019) Germinal Center B cell initiation, GC maturation, and the coevolution of its stromal cell niches. Immunological Reviews 288; 10-27.
Jain RW, Parham KA, Tesfagiorgis Y, Craig HC, Romanchik E, and Kerfoot SM. (2018) Autoreactive, low-affinity T cells preferentially drive differentiation of short-lived Memory B cells at the expense of germinal center maintenance. Cell Reports 25(12);3342-3355.
Gonzalez DG, Cote CM, Patel JR, Smith CB, Zhang Y, Nickerson KM, Zhang T, Kerfoot SM, and Haberman AM. (2018) Non-redundant roles of IL-21 and IL-4 in the phased initiation of germinal center B cells and subsequent self-renewal transitions. Journal of Immunology 201(12): 3569-3579.
Singh B, Summers KL, and Kerfoot SM. (2018) Novel Regulatory Th17 cells and Regulatory B cells in Modulating Autoimmune Diseases. Cellular Immunology 339: 29-32.
Tesfagiorgis Y, Zhu S, Jain R, and Kerfoot SM. (2017) Activated B cells participating in the anti-myelin response are excluded from the inflamed central nervous system in a model of autoimmunity that allows for B cell recognition of autoantigen. Journal of Immunology 199(2): 449-457.
Whittaker Hawkins R, Patenaude A, Dumas A, Jain R, Tesfagiorgis Y, Kerfoot S, Matsui T, Gunzer M, Poubelle P, Larochelle C, Pelletier M, and Vallières L. (2017) ICAM1+ neutrophils promote chronic inflammation via ASPRV1 in B cell-dependent autoimmune encephalomyelitis. JCI Insight 2(23); e9688
Zhang T, Gonzalez DG, Cote CM, Kerfoot SM, Deng S, Chen Y, and Haberman AM. (2017) Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help. eLife 6: e19552
Rangachari, M, Kerfoot SM, Arbour N, and Alvarez J. (2017) Editorial: More than a CD4+ world: a consideration of underappreciated lymphocyte subsets in multiple sclerosis and its animal models. Frontiers in Immunology 8:133.
Jain RW, Dang AK, and Kerfoot SM. (2016) Simple and effective production and purification of mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis. Journal of Visualized Experiments 116: e54727
Dang AK, Tesfagiorgis Y, Jain RW, Craig HC, and Kerfoot SM. (2015) Meningeal infiltration of the spinal cord by non-classically activated B cells is associated with chronic disease course in a spontaneous B cell-dependent model of CNS autoimmune disease. Frontiers in Immunology 6: 470.
Dang AK, Jain RW, Craig HC, and Kerfoot SM. (2015) B cell recognition of myelin oligodendrocyte glycoprotein autoantigen depends on immunization with protein rather than short peptide, while B cell invasion of the CNS in autoimmunity does not. Journal of Neuroimmunology 278C: 73-84.
Yamamoto N., Kerfoot S.M., Hutchinson A.T., DelaCruz C.S., Nakazawa N., Szczepanik M., Majewska-Szczepanik M., Nazimek K., Ohana N., Bryniarski K., Mori T., Muramatsu M., Kanemitsu K., Askenase P.W. (2015) Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: evidence of a subpopulation of protective anti-pneumococcal B1a B cells. Immunology 147(1): 97-133.
Askenase PW, Bryniarski K, Paliwal V, Redegeld F, Groot Kormelink T, Kerfoot S, Hutchinson AT, van Loveren H, Campos R, Itakura A, Majewska-Szczepanik M, Yamamoto N, Nazimek K, Szczepanik M, Ptak W. (2015) A subset of AID-dependent B-1a cells initiates hypersensitivity and pneumococcal pneumonia resistance. Annals of the New York Academy of Sciences; 1362(1): 200-214.
Kerfoot SM, Yaari G, Patel JR, Johnson KL, Gonzalez DG, Kleinstein SH, and Haberman AM. (2011) Germinal Center B cell and T Follicular Helper cell development initiates in the interfollicular zone. Immunity 34(6): 947-960.
Askenase PW, Majewska-Szczepanik M, Kerfoot S, and Szczepanik M. (2011) Participation of iNKT cells in the early and late components of Tc1 mediated DNFB contact sensitivity: Cooperative role of -T cells. Scandinavian Journal of Immunology 73(5):465-477
Hauser AE, Kerfoot SM, and Haberman AM. (2010) Cellular choreography in the germinal center: new visions from in vivo imaging. Seminars in Immunopathology 32(3): 239-255
Kerfoot SM, Szczepanik M, Tung JW, and Askenase PW. (2008) Identification of Initiator B cells, a novel subset of activation-induced deaminase-dependent B-1-like cells that mediate initiation of contact sensitivity. Journal of Immunology 181(3):1717-1727.
Kerfoot SM, Andonegui G, Bonder C. and Liu L. (2008) Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo. AJP: Heart and Circulatory Physiology 294: H2524-H2534.
Pedra JHF, Mattner J, Tao J, Kerfoot SM, Davis RJ, Flavell RA, Askenase PW, Yin Z, and Fikrig E. (2008) c-Jun NH2-terminal kinase 2 inhibits gamma interferon production during Anaplasma phagocytophilum infection. Infection and Immunity 76(1): 308-316
Kerfoot SM, McRae K, Lam F, McAvoy EF, Clark S, Brain M, Lalor PF, Adams DH and Kubes P. (2008) A novel mechanism of senescent erythrocyte capture from the circulation in humans. Experimental Hematology 36(2): 111-118.
Kerfoot SM, Norman MU, Lapointe BM, Bonder CS, Zbytnuik L, and Kubes P. (2006) Re-evaluation of P-selectin and 4-integrin as targets for the treatment of experimental autoimmune encephalomyelitis. Journal of Immunology 176(10): 6225-6234
Kerfoot SM, Norman MU, Lapointe BM, Bonder CS, Zbytnuik L, and Kubes P. (2006) Re-evaluation of P-selectin and 4-integrin as targets for the treatment of experimental autoimmune encephalomyelitis. Journal of Immunology 176(10): 6225-6234
Kerfoot SM, D’Mello C, Nguyen H, Ajuebor MN, Kubes P, Le T, Swain MG. (2006) TNFα-secreting monocytes are recruited into the brain of cholestatic mice. Hepatology 43(1): 154-162
Kerfoot SM and Kubes P. (2005) Local coordination verses systemic disregulation: Complexities in leukocyte recruitment revealed by local and systemic activation of TLR4 in vivo. Journal of Leukocyte Biology 77: 862-867.
Andonegui G, Kerfoot SM, McNagny K, Ebbert KV, Patel KD, and Kubes P. (2005) Platelets express functional toll-like receptor-4 (TLR4). Blood 106(7): 2417-2423.
Khan AI, Kerfoot SM, Heit B, Liu L, Andonegui G, Ruffell B, Johnson P, and Kubes P. (2004) Role of CD44 and hyaluronan in neutrophil recruitment. Journal of Immunology 173(12): 7594-7601.
Kerfoot SM, Long EM, Hickey MJ, Andonegui G, Lapointe BM, Zanardo RCO, Bonder C, James WG, Robbins SM, and Kubes P. (2004) TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease. Journal of Immunology 173(11): 7070-7077.
Kerfoot SM, Lord SE, Bell RB, Gill V, Robbins SM, and Kubes P. (2003) Human fractalkine mediates leukocyte adhesion but not capture under physiological shear conditions; a mechanism for selective monocyte recruitment. European Journal of Immunology 33(3): 729-739.
Kerfoot SM and Kubes P. (2002) Overlapping roles of P-selectin and alpha4-integrin to recruit leukocytes to the CNS in experimental autoimmune encephalomyelitis. Journal of Immunology 169(2): 1000-1006.
Kubes P and Kerfoot SM. (2001) Leukocyte recruitment in the microcirculation: the rolling paradigm revisited. News in Physiological Science 16: 76-80
Kerfoot SM, Raharjo E, Ho M, Kaur J, Serirom S, McCafferty DM, Burns AR, Patel KD, Kubes P. (2001) Exclusive neutrophil recruitment with Oncostatin M in a human system. American Journal of Pathology 159(4): 1531-1539.
Fritzler MJ, Kerfoot SM, Feasby TE, Zochodne DW, Westendorf JM, Dalmau JO, and Chan EKL. (2000) Autoantibodies from patients with idiopathic ataxia bind to M-phase phosphoprotein-1 (MPP1). Journal of Investigative Medicine 48(1): 28-39.
